Understanding ALS

Disease Directed Therapy

Rilutek (Riluzole)

The only drug approved to specifically treat ALS as of now is Rilutek. Studies performed showed that Rilutek helped to protect nerve cells from damage likely by reducing the amount of glutamate in the nervous system. It is important to understand that Rilutek will not restore any loss of function prior to the start of treatment. It only slows progression. The recommended dosage for Rilutek is 50mg (one tablet) every 12 hours. The medication should be taken the same time every day such as every morning and night. Rilutek should be taken at least one hour after meals. The most common side effects of Rilutek are weakness, nausea, dizziness, headache and elevation of liver enzymes. If there is nausea, your doctor may recommend that the medicine be taken with meals. It is not recommended that you smoke or drink excessive amounts of alcohol while taking this medication. Smoking may decrease the amount of Rilutek in your bloodstream. Alcohol may contribute to elevated liver enzymes and may cause an increase risk of liver problems while taking Rilutek.